Node-Positive Breast Cancer: Which Are the Best Chemotherapy Regimens?
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چکیده
منابع مشابه
Node-positive Breast Cancer: Which Are the Best Chemotherapy Regimens?
Breast cancer-associated mortality has been significantly reduced since the 1990s, mainly because of early diagnosis and systemic therapeutic interventions. All three therapy components - cytostatic therapy, endocrine therapy and targeted antibody therapy - are at present necessary tools for the curative treatment of primary breast cancer. This article reviews the evidence base for the use of v...
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The goal of screening for breast cancer is to identify cancers when they are at a curable stage. The prospect for cure depends in turn on the extent to which the cancer has spread at diagnosis. If a breast cancer is entirely contained within the breast (that is, if no subclinical metastases have occurred), then complete excision through mastectomy or breastconserving surgery is expected to be c...
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BACKGROUND We compared docetaxel plus doxorubicin and cyclophosphamide (TAC) with fluorouracil plus doxorubicin and cyclophosphamide (FAC) as adjuvant chemotherapy for operable node-positive breast cancer. METHODS We randomly assigned 1491 women with axillary node-positive breast cancer to six cycles of treatment with either TAC or FAC as adjuvant chemotherapy after surgery. The primary end p...
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Adjuvant chemotherapy for early breast cancer patients improves survival in general, but estimating true benefit on the individual level remains a challenge, especially for older individuals. There are some data suggesting that older individuals, certainly those at higher risk of relapse, can indeed derive benefit from adjuvant chemotherapy, and this therapy should certainly not be denied on th...
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ژورنال
عنوان ژورنال: Breast Care
سال: 2008
ISSN: 1661-3805,1661-3791
DOI: 10.1159/000149099